In the latest version of CYPE (version 2020.f), the new Open BIM COVID-19 program was published, a tool created to develop prevention plans against the spread of the SARS-CoV-2 virus in open places and buildings, such as shops, schools, offices, restaurants etc. The application, which is free, supports different workflows and allows even users who are not familiar with Open BIM technology to carry out their prevention projects. In this article, we cite 6 workflows that combine different formats and tools, and that can be adopted when working with Open BIM COVID-19.